Preliminary Program
Monday 16 September 2024
Opening ceremony and Keynote lectures
15.00-15.45 | A historical perspective of the Maillard reaction, Prof. Dr. Monnier, Cleveland, USA
15.45-16.20 | RAGE/DIAPH1: Implications for the Mechanisms and Treatment of Cardiometabolic Disease, Prof. Dr. Schmidt, New York, USA
16.20-16.55 | The fate of dietary AGE in the gastrointestinal tract, Prof. Dr. Fogliano, Wageningen, the Netherlands
18.00 | Reception, Town hall Maastricht
Tuesday 17 September 2024
Scientific Sessions 1: RAGE in health & disease
This session will be chaired by: Dr. Wouters and Prof. Inagi
Invited Speakers
08.30-08.55 | Activation of RAGE in diabetes and its complications; a therapeutic target, Prof. Dr. Cooper, Melbourne, Australia
08.55-09.20 | The impact of RAGE for oxytocin dynamics in the body and brain, Prof. Dr. Yamamoto, Kanazawa, Japan
Oral presentations
09.20-09.35 | Targeting RAGE using an oral antagonist to prevents Type 1 diabetes via attenuation of effector T cell responses in a preclinical model, J. Forbes, Brisbane, Australia
09.35-09.50 | RAGE-antagonism by Azeliragon counteracts diet-induced adiposity in mice through improvement of lipid metabolism and reduction of inflammation, R. Mastrocola, Turin, Italy
09.50-10.05 | Plasma advanced glycation end-products, sRAGE, and bone mineral density in girls with anorexia nervosa, K. Šebeková, Bratislava, Slovakia
10.05-10.30 | Break
Scientific Sessions 2: Dicarbonyl stress (1)
This session will be chaired by: Prof. Pischetsrieder and Prof. Rabbani
Invited Speakers
10.30-10.55 | |Methylglyoxal stress in diabetes and its complications, Prof. Dr. Thornalley, Doha, Qatar
10.55-11.20 | Methylglyoxal adducts in diabetic complications, Dr. Shuck, Duarte, USA
Oral presentations
11.20-11.35 | Association between liver fat accumulation and glyoxalase I activity loss, independent of serum dicarbonyls, in humans,
E. Schleicher, Tuebingen, Germany
11.35-11.50 | Investigating the effects of methylglyoxal stress on immune response to tumors, V. Mohring, Liège, Belgium
11.50-12.05 | Loss of NAMPT and SIRT2 but not SIRT1 Attenuate GLO1 Expression and Activity in Human Skeletal Muscle, J. Haus, Michigan, USA
12.05-14.00 | Lunch and poster session
Scientific Sessions 3: Dietary AGEs (1)
This session will be chaired by: Prof. Fogliano and Prof. Nissen Lund
Invited Speakers
14.00-14.25 | The impact of dietary advanced glycation endproducts, Dr. Linkens, Maastricht, the Netherlands
14.25-14.50 | Ultra-processed foods and adverse health effects: many mechanistic hypotheses - including glycation - but what is the scientific evidence? Prof. Tessier, Lille, France
Oral presentations
14.50-15.05 | The Food Glycation Database: an on-line tool to investigate the role of processing and dietary AGEs nutritional implications,
A. Fiore, Dundee, United Kingdom
15.05-15.20 | Analysis of advanced glycation end products in differently processed pet foods by ultra-high performance liquid chromatography tandem mass spectrometry and association of dietary intake with plasma and urine advanced glycation end products in healthy dogs,
S. Bridglalsingh, Georgia , USA
15.20-15.35 | Dietary Maillard reaction products N-ε-carboxymethyllysine, N-ε-fructosyllysine and pyrraline in mice: absorption, distribution and their effects on inflammation and oxidative stress, J. Raupbach, Braunschweig, Germany
15.35-16.00 | Break
Scientific Sessions 4: Dicarbonyl stress (2)
This session will be chaired by: Prof. Thornalley and Dr. Haus
Invited Speakers
16.00-16.25 | Methylglyoxal Metabolism: Navigating the Path from the Known to the Unknown, Dr. Fleming, Heidelberg, Germany
16.25-16.50 | Dietary dicarbonyls: friends or foes of human health? Dr. Maasen, Utrecht, the Netherlands
Oral presentations
16.50-17.05 | On the effect of methylglyoxal on the structure, function and aggregation propensity of alpha-synuclein, M. Adrover, Palma de Mallorca, Balearic Islands, Spain
17.05-17.20 | Changes in the exo-loop residue T107 alters the activity and function of Glyoxalase 1, A. Dimitropoulos, Melbourne, Australia
17.20-17.35 | Glyoxalase-1 overexpression attenuates arterial stiffness in a mouse model of diabetes, M. Pencheva, Maastricht, the Netherlands
18.30 | Congress Dinner, Ipanema aan de Maas
Wednesday 18 September 2024
Scientific Sessions 5: Analysis of AGEs (1)
This session will be chaired by: Dr. Fleming and Prof. Nagai
Invited Speakers
08.30-08.55 | Detection of (pre-)AGEs: a critical appraisal, Dr. Scheijen, Maastricht, the Netherlands
08.55-09.20 | Maillard reaction products and amino acid cross-links and the effect of heat treatment and storage conditions, Prof. Nissen Lund, Frederiksberg, Denmark
Oral presentations
09.20-09.35 | Clinical validation of plasma glycated amino acid-based blood test for early-stage osteoarthritis, A. Al-Saei, Doha, Qatar
09.35-09.50 | Profiling of glycation products in an untargeted metabolomics approach , Y. Yan, Neuherberg, Germany
09.50-10.05 | Glycation biomarkers in diabetic patients’ fingernails – LC-MS/MS quantification of early and advanced glycation products in an underexploited, non-invasive biological matrix, M. Howsam, Lille, France
10.05-10.30 | Break
Scientific Sessions 6: AGEs and mental disorder
This session will be chaired by: Prof. Sebekova and Prof. Kankova
Invited Speakers
10.30-10.55 | The Impact of AGEs in Mental Disorders, Prof. Dr. Arai, Tokyo, Japan
10.55-11.20 | Methylglyoxal stress regulating the immune landscape in breast cancer, Prof. Bellahcene, Liege, Belgium
Oral presentations
11.20-11.35 | A maternal diet enriched in advanced glycation end-products reduces impulsive and anxiety-like behavior and increases adiposity in female offspring, M. Klug, Los Angeles, USA
11.35-11.50 | Glyoxalase 1 overexpression improves neurovascular coupling response and reduces cognitive decline in an animal model of type 1 diabetes, E. Berends, Maastricht, the Netherlands
11.50-12.05 | Glycation reduces albumin's protective effect against amyloid-β: Insights for Brain Health, M. Chrysanthou, Wageningen, the Netherlands
12.05-14.00 | Lunch and poster session
Scientific Sessions 7: AGEs and microbiome
This session will be chaired by: Dr. Teodorowicz and Dr. Mastrocola
Invited Speakers
14.00-14.25 | Exploring the Impact of Glucagon-like Peptide-1 Receptor Signaling on RAGE-Mediated Inflammation, Prof. Dr. Coughlan, Melbourne, Australia
14.25-14.50 | Methylglyoxal and complications: a role of the microbiome? Dr. Hanssen, Amsterdam, the Netherlands
Oral presentations
14.50-15.05 | Gut bacterium Intestinimonas butyriciproducens improves host metabolic health: evidence from cohort and animal intervention studies, N. Bui, Amsterdam, the Netherlands
15.05-15.20 | Metabolization of the Amadori Product N-ε-Fructosyllysine by Probiotic Bacteria, L. Filipp, Dresden, Germany
15.20-15.35 | How do early and lifelong exposure to dietary AGEs affect tissue, gut sensitivity, and microbiota in mice?, M. Nogueira Silva Lima, Lille, France
16.00 | Social Programme
Thursday 19 September 2024
Scientific Sessions 8: Analysis of AGEs (2)
This session will be chaired by: Prof. Monnier and Prof. Forbes
Invited Speakers
08.30-08.55 | The impact of glycation and succination in health and disease, Prof. Dr. Nagai, Kamimashiki-gun, Japan
08.55-09.20 | Detection of AGEs with SAF in age-related diseases; an epidemiological approach, Prof. Dr. Zillikens, Rotterdam, the Netherlands
Oral presentations
09.20-09.35 | The impact of different glycation methods on the immunomodulatory effects of human serum albumin, C. Croes, Wageningen, the Netherlands
09.35-09.50 | Glycation and aldosterone antagonistic interactions inhibit the progression of diabetic nephropathy and cardiomyopathy in streptozotocin-induced diabetic BALB/c mice, R. Tupe, Pune, India
09.50-10.05 | Inflammation drives increased chemical modification of proteins by fumarate and itaconate, N. Frizzell, Columbia, SC, USA
10.05-10.30| Break
Scientific Sessions 9: Dietary AGEs (2)
This session will be chaired by: Prof. Fiore
Invited Speakers
10.30-10.55 | The impact of acrylamide and other potentially toxic MRPs, Prof. Gökmen, Ankara, Turkey
10.55-11.20 | Unravelling the paradox: dietary methylglyoxal a cure for diabetes? Dr. Vangrieken, Maastricht, the Netherlands
Oral presentations
11.20-11.35 | Biodegradation of food melanoidins via solid state fermentation by Aspergillus awamori, S. Yang, Wageningen, the Netherlands
11.35-11.50 | Inhibitory Potential of Vitamins on Heat-Induced Protein Modifications in Whey-Based Foods, T. Schichtl, Erlangen, Germany
11.50-12.05 | Key Contributors to Color Formation? – Elucidating the Role of Short-Chained Maillard Reaction Products in Melanoidin Formation,
C. Kanzler, Berlin, Germany
12.05-13.00 | Final and farewell